Sr. / Director Global Regulatory Affairs - Gene Therapy

Salary $255,000 - $320,000 dependent on level
LocationPrinceton, New Jersey
Employment type Permanent
Discipline

Job description

A global biopharmaceutical organization focused on serious and rare diseases is seeking a Global Regulatory Lead (GRL) to lead global programs across their gene therapy pipeline. The company values meaningful work, collaboration, and a culture where curiosity and impact are central.

Role Overview
The GRL develops and drives global regulatory strategies, guides cross-functional teams through development and submission activities, and leads interactions with U.S. and global Health Authorities. The role oversees regulatory submissions, agency communications, and risk-mitigation planning across assigned programs.

Key Responsibilities
•     Lead global regulatory strategy across clinical, preclinical, and lifecycle activities
•     Identify regulatory risks and define mitigation approaches
•     Advise on IND and CTA strategies and support cross-functional teams
•     Direct planning and preparation of global submissions and briefing packages
•     Oversee materials for regulatory meetings and deliver clear, high-quality presentations
•     Monitor global regulatory trends and assess impact on programs
•     Collaborate effectively with regional regulatory leads and matrixed teams

Qualifications
•     Bachelor’s degree in life sciences required; advanced degree preferred
•     5+ years in Regulatory Affairs with global submission experience
•     2+ years in Gene Therapy Required
•     Strong knowledge of global requirements and eCTD formats
•     Proven ability to manage complex regulatory deliverables
•     Experience with orphan drug products preferred; inhalation experience a plus
•     Significant interaction with major global regulatory agencies
•     Highly organized, detail?oriented, and able to manage tight timelines