Sr. Manager, CDM

Salary $90-$100 /hr
LocationSan Francisco, California
Employment type Contract
Discipline
Life Sciences

Job description

Sr. Manager, CDM 
Location: South San Francisco, 3 days onsite 
Pay Rate: $90-$100/hr 
Duration: 6 months

A leading biotechnology organization is seeking a Contract Senior Manager, Clinical Data Management to oversee data management activities across one or more clinical studies, from initiation through closure. This role ensures timely, high-quality data delivery aligned with project goals and budget. The Senior Manager will report to the Head of Clinical Data Management and collaborate with cross-functional teams in a dynamic, fast-paced environment.

Key Responsibilities

  • Lead Electronic Data Capture (EDC) development, including CRF design, specifications, edit checks, and User Acceptance Testing (UAT) documentation.
  • Review and support development of study documents from CROs, such as data transfer agreements, eCRF Completion Guidelines, and Data Management Plans.
  • Ensure data quality through rigorous review and reconciliation processes; communicate and resolve outstanding issues.
  • Collaborate with CROs to develop clean patient trackers.
  • Coordinate SAS dataset transfers and electronic data exchanges.
  • Manage rolling and final database lock processes.
  • Monitor and audit data management deliverables to ensure quality and compliance.
  • Maintain adherence to regulatory standards (ICH, GCP), internal SOPs, and industry best practices.
  • Oversee CRO vendor performance to ensure accurate and timely data delivery.
  • Serve as the primary data management contact for assigned studies.
  • Participate in team meetings and proactively raise data-related risks and concerns.

Qualifications

  • Bachelor’s degree in life sciences, computer science, or related field.
  • 10–12+ years of experience in pharmaceutical or CRO settings, managing Phase I–III studies.
  • Proficiency in multiple EDC systems within the past 3 years.
  • Strong expertise in clinical data management processes; certification preferred.
  • Experience managing external EDC vendors; build experience a plus.
  • Familiarity with CDISC, CDASH, SAS® terminology, and coding standards (MedDRA, WHODRUG, CTCAE).
  • Deep understanding of regulatory guidelines and data standards.
  • Exceptional organizational skills and attention to detail.
  • Strong communication and interpersonal abilities.
  • Capable of managing multiple priorities and projects independently.
  • Comfortable engaging with stakeholders at all organizational levels.
  • Proficient in Microsoft Office Suite (Word, Excel, PowerPoint, Project)